SCOPE

Compound Toxicity Profile  (CTP) is part of our toxicological investigation service and consists of statistical toxicity models that generate profiles for chemicals and subsequent toxicity alerts in diverse areas :

    • Neurotoxicity
    • Reprotoxicity
    • Carcinogenicity
    • Mutagenicity
    • Endocrine disruption
    • Persistent-Bioaccumulative Toxicity (PBT)
    • Skin sensitization
    • Inhalation sensitization

APPLICATION

We address the needs of clients, subject or not to the REACH regulation, by providing a rationale to support decision-making processes :

  • Generate toxicity alerts : statistical QSAR models are trained to recognize compounds with a toxicity issue based on structural descriptors
  • Prioritize the most promising compounds at an early stage by discarding chemicals with toxicity bottlenecks 
  • Substitute compounds for more compliant ones : Our models can also be  used to select a safer compound in a more advanced development stage

BENEFITS

By ensuring safety of chemicals, we provide additional pieces of a rationale for making decisions :

    • Reduce overall costs of development by supporting decisions at critical stages
    • Comply with the REACH and other regulations
    • Comply with the trend of less animal testing

For more details please contact us !